Table S3. IUP_list
List of 129 proteins with experimentally verified disorder status. Proteins are enlisted with their identification (Swissprot, translated EMBL or Genbank number), sequence range of disorder and reference to disorder.
All IUP sequences (129 proteins or protein fragments)
protein |
Prot id. |
Sequence range |
reference(s) |
ICAL_HUMAN |
sp|P20810| |
1-708 |
Uemori T. et al. (1990) Biochem. Biophys. Res. Commun. 166, 1485 Konno T. et al. (1997) Biochim. Biophys. Acta 1342, 73 |
CDNB_HUMAN |
sp|P46527| |
1-198 |
Russo, A. A. et al. (1996) Nature 382, 325-31 Verkhivker, G. M. et al. (2003) Proc. Natl. Acad. Sci. USA 100, 5148-53 Lacy, E. R. et al. (2004) Nat. Struct. Mol. Biol. 11, 358-64 |
IPPD_HUMAN |
sp|Q9UD71| |
1-204 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
SECU_XELA |
tr|Q9IA80| |
1-188 |
Cox C. J. et al. (2002) FEBS Lett. 527, 303-308 Boatright K., unpublished observations |
FLGM_ECOLI |
sp|P43532| |
1-97 |
Daughdrill, G. W. et al. (1997) Nat. Struct. Biol. 4, 285-91 Daughdrill, G. W. et al. (1998) Biochemistry 37, 1076-82 |
THYA_HUMAN |
sp|P06454| |
1-110 |
Gast, K. et al. (1995) Biochemistry 34, 13211-8 Gast, K. et al. (2003) Eur. Biophys. J. 31, 586-94 |
CMGA_HUMAN |
sp|P10645| |
19-457 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
SYUA_HUMAN |
sp|P37840| |
1-140 |
Weinreb, P. H. et al. (1996) Biochemistry 35, 13709-15 |
FNBA_STAAU |
sp|P14738| |
745-879 |
Penkett, C. J. et al. (1997) J. Mol. Biol. 274, 152-9 Penkett, C. J. et al. (1998) Biochemistry 37, 17054-67 |
TAU_HUMAN |
sp|P10636| |
1-757 |
Schweers, O. et al. (1994) J. Biol. Chem. 269, 24290-7 |
MAP2_HUMAN |
sp|P11137| |
1-1827 |
Hernandez, M. A. et al. (1986) Eur. J. Biochem. 1564, 41-8 |
STN1_HUMAN |
sp|P16949| |
1-148 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
CALD_HUMAN |
sp|Q05682| |
1-793 |
Lynch, W. P. et al. (1987) J. Biol. Chem. 262, 7429-37 Huber, P. A. (1997) Int. J. Biochem. Cell Biol. 29, 1047-51 Permyakov, S. E. et al. (2003) Proteins53, 855-62 |
OBF1_HUMAN |
sp|Q16633| |
1-256 |
Chang, J. F. et al. (1999) J. Mol. Biol. 288, 941-52 |
HIBN (X. laevis) |
sp|P06180| |
1-589 |
Kleinschmidt J. A. et al. (1986) Embo J. 5, 3547-3552 |
OSTP_HUMAN |
sp|P10451| |
17-314 |
Fisher L. W. et al. (2001) Biochem. Biophys. Res. Commun. 280, 460-465 |
CDNA_HUMAN |
sp|P38936| |
1-164 |
Kriwacki, R. W. et al. (1996) Proc. Natl. Acad. Sci. USA 93, 11504-9 |
VAM1_HUMAN |
sp|P23763| |
1-97 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573 |
PRIO_HUMAN |
sp|P04156| |
23-122 |
Zahn C. et al. (2000) Proc. Natl. Acad. Sci. USA 97, 145-50 Donne, D. G. et al. (1997) Proc. Natl. Acad. Sci. USA 94, 13452-7 |
GCN4_YEAST |
sp|P03069| |
211-281 |
Van Hoy, M. et al. (1993) Cell 72, 587-94 Weiss, M. A. et al. (1990) Nature 347, 575-8 Sigler, P. B. (1988) Nature 333, 210-2 |
TBB1_HUMAN |
sp|P07437| |
398-444 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
EMB1_DAUCA |
sp|P17639| |
1-92 |
Eom, J. et al. (1996) Plant Sci. 115, 17-24 |
ATIN_HHV11 |
sp|P06492| |
403-490 |
O'Hare, P. and Williams, G. (1992) Biochemistry 31, 4150-6 Sigler, P. B. (1988) Nature 333, 210-2 |
HtH (H. salinarum) |
tr|O06022| |
1-451 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
TRIC_HUMAN |
sp|P19429| |
1-209 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
GAGA_DROME |
sp|Q08605| |
136-519 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
HSP2_HUMAN |
sp|P04554| |
1-102 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
H10_HUMAN |
sp|P07305| |
1-193 |
Uversky V. N. (2000) Proteins 41, 415-427 |
HSP3_MOUSE |
sp|Q62100| |
1-102 |
Uversky V. N. (2000) Proteins 41, 415-427 |
Helix destab. (P. aeruginosa) |
tr|Q9I5K8| |
1-144 |
Uversky V. N. et al. (2002) Prot. Sci. 11, 739-756 |
GSUB_HUMAN |
sp|O96001| |
1-155 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
GELS_HUMAN |
sp|P06396| |
200-273 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
EM1_WHEAT |
sp|P04568| |
1-93 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
FOS_HUMAN |
sp|P01100| |
216-380 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
TOXK_PICFA |
sp|P19972| |
146-222 |
Suzuki C. et al (1997) Prot. Eng. 10, 99-101 |
DAG1_MOUSE |
sp|Q62165| |
654-751 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
CRTC_HUMAN |
sp|P27797| |
18-417 |
Uversky V. N. (2002) Prot. Sci. 11, 739-756 |
SUPM_HUMAN |
sp|P50224| |
216-262 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
CFTR_HUMAN |
sp|P13569| |
708-832 |
Ostedgaard L. S. (2000) Proc. Natl. Acad. Sci. USA, 97, 5657-5662 |
NEUM_BOVIN |
sp|P06836| |
1-239 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
PID1_RAT |
sp|P10688| |
135-206 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
CIK1_HUMAN |
sp|Q09470| |
1-63 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
RPB1_YEAST |
sp|P04050| |
1436-1733 |
Zhang J and Corden J. L. (1991) J. Biol. Chem. 266, 2290-2296 Zhang J. and Corden J. L. (1991) J. Biol. Chem. 266, 2297-2302 Cramer P. et al. (2001) Science 292, 1863-1876 |
SRY_MOUSE |
sp|Q05738| |
144-395 |
Tompa, P., unpublished observations |
WAS1_HUMAN |
sp|Q92558| |
230-311 |
Kim A. S. et al. (2000) Nature 404, 151-158 |
BN28a (B. napus) |
tr|Q9FUM5| |
1-65 |
Boothe J. G. et al. (1997) Plant Physiol. 113, 367-376 |
NPM3_HUMAN |
sp|O75607| |
1-178 |
Dingwall C. et al. (1987) Embo J. 6, 69-74 |
MPT1_HUMAN |
sp|O14974| |
304-512 |
Tóth A. et al. (2000) Eur. J. Biochem. 267, 1687-97 Tompa P., unpublished observations |
Calpain (D. melanogaster) |
tr|O96454| |
135-227 |
Tompa, P., unpublished observations |
Pp1 reg. sub. (H. sapiens) |
tr|O60927 |
1-126 |
Zhang J. et al. (1998) Biochemistry 37, 16728-16734 |
MACS_BOVIN |
sp|P12624| |
1-331 |
Manenti S. et al. (1993) J. Biol. Chem. 268, 6878-6881 |
CAD1_MOUSE |
sp|P09803| |
734-884 |
Huber, A. H. et al. (2001) J. Biol. Chem. 276, 12301-9 |
INVO_HUMAN |
sp|P07476| |
1-585 |
Etoh Y. et al. (1986) Biochem. Biophys. Res. Commun. 136, 51-56 Eckert R. L. and Green H. (1986) Cell 46, 583-589 Rice R. H. and Green H. (1984) Cell 18, 681694 |
HS9A_CHICK |
sp|P11501| |
227-293 |
Csermely P. and Tompa, P., unpublished observations |
NUP2_YEAST |
sp|P32499| |
1-720 |
Denning D. P. et al. (2002) J. Biol. Chem. 277, 33447-33455 Denning D. P. et al. (2002) Proc. Natl. Acad. Sci. USA 100, 2450-2455 |
DH10_ARATH |
sp|P42759| |
1-260 |
Tompa P., unpublsihed observations |
CGB1_HUMAN |
sp|P14635| |
1-121 |
Cox C. J. et al. (2002) FEBS Lett. 527, 303-308 |
COA1_SV40 |
sp|P03087| |
299-364 |
Liddington R. C. et al. (1991) Nature 354, 278-284 |
ITF2_HUMAN |
sp|P15884| |
1-131 |
Knapp S. et al. (2001) J. Mol. Biol. 306, 1179-89 |
EPN1_RAT |
sp|O88339| |
144-575 |
Kalthoff C. et al. (2002) J. Biol. Chem. 277, 8209-8216 |
A180_MOUSE |
sp|Q61548| |
328-901 |
Kalthoff C. et al. (2002) J. Biol. Chem. 277, 8209-8216 |
IPA3_YEAST |
sp|P01094| |
1-68 |
Li M. et al. (2000) Nat. Struct. Biol. 7, 113-117 |
CAS1_MOUSE |
sp|P19228| |
16-313 |
Bhattacharyya, J. and Das, K. P. (1999) J. Biol. Chem. 274, 15505-15509 |
CASB_HUMAN |
sp|P05814| |
16-226 |
Holt C. et al. (1993) J. Chem. Soc. Faraday Trans.89, 2683 Syme C. D. et al. (2002) Eur. J. Biochem. 269, 148 |
CASK_HUMAN |
sp|P07498| |
21-182 |
Holt C. et al. (1993) J. Chem. Soc. Faraday Trans.89, 2683 Syme C. D. et al. (2002) Eur. J. Biochem. 269, 148 |
4BP1_MOUSE |
sp|Q60876| |
1-117 |
Fletcher, C. M. and Wagner, G. (1998) Prot. Sci. 7, 1639-42 |
IPKA_HUMAN |
sp|P61925| |
1-75 |
Hauer, J. A. et al. (1999) Biochemistry 38, 6774-80 Hauer, J. A. et al. (1999) Prot. Sci. 8, 545-53 |
PRG (H. sapiens) |
tr|Q04118| |
1-309 |
Muenzer, J. et al. (1979) J. Biol. Chem. 254, 5629-34 Loomis, R. E. et al. (1985) Int. J. Pept. Prot. Res. 26, 621-629 |
REGN_LAMBD |
sp|P03045| |
1-107 |
Greenblatt J. and Li J. (1982) J. Biol. Chem. 257, 362-5 Van Gilst M. R. and von Hippel, P. H. (1997) J. Mol. Biol. 274, 160-73 |
CREB_HUMAN |
sp|P16220| |
4-266 |
Radhakrishnan, I. et al. (1998) FEBS Lett. 430, 317-22 |
TTF1 (H. sapiens) |
tr|O14956| |
1-125 |
Tell, G. et al. (1998) Biochem. J. 329, 395-403 |
RLA3_YEAST |
sp|P10622| |
1-106 |
Zurdo, J. et al. (2000) Biochemistry 39, 8935-43 |
CDNC_HUMAN |
sp|P49918| |
1-316 |
Adkins, J. N. and Lumb, K. J. (2002) Proteins 46, 1-7 |
FLIC_SALTY |
sp|P06179| |
1-66 |
Gugolya, Z. et al. (2003) FEBS Lett. 535, 66-70 |
NFH_MOUSE |
sp|P19246| |
409-1087 |
Brown, H. G. and Hoh, J. H. (1997) Biochemistry 36, 15035-40 |
P53_HUMAN |
sp|P04637| |
1-74 |
Bell, S. et al. (2002) J. Mol. Biol. 322, 917-27 Dawson, R. et al. (2003) J. Mol. Biol. 332, 1131-41 |
XPA_XENLA |
sp|P27088| |
1-85 |
Iakoucheva, L. M. et al. (2001) Prot. Sci. 10, 560-71 |
Titin (H. sapiens) |
tr|Q8WZ42| |
9880-12031 |
Li, H. et al (2001) Proc. Natl. Acad. Sci. USA 98, 10682-6 Ma, K. and Wang, K. (2003) Biochem J. 374, 687-95 Trombitas, K. et al. (1998) J. Cell. Biol. 140, 853-9 |
LEA1_APHAV |
sp|Q95V77| |
1-143 |
Soulages, J. L. et al. (2002) Plant Physiol. 128, 822-32 Goyal, K. et al. (2003) J. Biol. Chem. 278, 12977-12984 |
HSF_YEAST |
sp|P10961| |
1-168 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
I4G1_HUMAN |
sp|Q04637| |
589-687 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
HG17_HUMAN |
sp|P05204| |
1-89 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
LEF1_MOUSE |
sp|P27782| |
296-381 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
NZFF1 (R. norvegicus) |
tr|P70475| |
487-608 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
TOP1_HUMAN |
sp|P11387| |
1-198 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
GCR_HUMAN |
sp|P04150| |
73-263 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
MAX_FELCA |
sp|P61245| |
1-160 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
SEC9_YEAST |
sp|P40357| |
407-651 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
SP2D_HUMAN |
sp|P22532| |
1-72 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
SdrD ( S. aureus) |
tr|O86488| |
550-1124 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
HRP II (P. falciparum) |
tr|P90582| |
1-309 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
MBP_BOVIN |
sp|P02687| |
1-169 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
PTHR_HUMAN |
sp|P12272| |
35-177 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
SPRC_HUMAN |
sp|P09486| |
18-88 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RL2_SHIFL |
sp|P60429| |
1-272 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RL27_ECOLI |
sp|P02427| |
1-84 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RL31_ECOLI |
sp|P02432| |
1-70 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RL32_ECOLI |
sp|P02435| |
1-56 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RL33_ECOLI |
sp|P02436| |
1-54 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RS12_ECOLI |
sp|P02367| |
1-123 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RS18_ECOLI |
sp|P02374| |
1-74 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RS19_ECOLI |
sp|P02375| |
1-91 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
RS21_ECOLI |
sp|P02379| |
1-70 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
TAF1_DROME |
sp|P51123| |
11-78 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
NEF_HV112 |
sp|P04324| |
1-206 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
SN25_CHICK |
sp|P60878| |
1-206 |
Uversky V. N. et al. (2000) Proteins 41, 415-427 |
TF65_HUMAN |
sp|Q04206| |
428-551 |
Uversky V. N. (2002) Prot. sci. 11, 739-756 |
SUBT_BACAM |
sp|P00782| |
33-108 |
Uversky V. N. (2002) Prot. sci. 11, 739-756 |
Tropomodulin (G. gallus) |
tr|Q91006| |
1-92 |
Uversky V. N. (2002) Prot. sci. 11, 739-756 |
HIS1_HUMAN |
sp|P15515| |
20-57 |
Uversky V. N. (2002) Prot. sci. 11, 739-756 |
AP1_HUMAN |
sp|P05412| |
257-315 |
Uversky V. N. (2002) Prot. sci. 11, 739-756 |
FA39_HUMAN |
sp|P49913| |
134-170 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
H3T_HUMAN |
sp|Q16695| |
1-40 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
H5_CHICK |
sp|P02259| |
101-186 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
RFA1_HUMAN |
sp|P27694| |
109-169 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
RGS4_RAT |
sp|P49799| |
1-60 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
CLUS_RAT |
sp|P05371| |
386-446 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
EFG_THETH |
sp|P13551| |
401-481 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
GLMT_RAT |
sp|P13255| |
1-40 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
SYG_THETH |
sp|P56206| |
95-158 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
DHB1_HUMAN |
sp|P14061| |
285-327 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
APE1_HUMAN |
sp|P27695| |
1-41 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
HSP_CHICK |
sp|P15340| |
1-61 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
COAT_TBSVB |
sp|P11795| |
1-101 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
MYC_HUMAN |
sp|P01106| |
1-144 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
Bcl-2 (H. sapiens) |
gb |1G5MA| |
24-93 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
POLS_SINDO |
sp|P27285| |
1-106 |
Dunker A. K. et al. (2002) Biochemistry 41, 6573-6582 |
Gliotactin (D. melanogaster) |
tr|Q9NK80| |
750-956 |
Zeev-Ben-Mordehai T. et al. (2003) Proteins 53, 758-67 |
Dsp-16 |
gb |AAA63613.1| |
1-155 |
Lisse, T. et al. (1996) Biol. Chem. 377, 555-61 |